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xn砾

时间 : 2009-12-07 05:21:31 来源:homepage.vghtpe.gov.tw

[摘要]

eēGxn砾oネvC10UH~Τ@HAキАき~sv13.7%CfzW82%涪砾

MI]lGx挡ホ]ぷㄤWL3そだ|^BC┦摸端H┪捌摸端Ha]chronictyphoidorparatyphoidcarrier^Bj1そだxnψBホηてxn]porceleinGB^C

{gGkW浮场khB独nB激ぃㄎB砰UBoNC

E_GWi匡uㄣC合@瘤Mゑ耕庇PAOO蔼CCEABCA199L基

TNMStagingforPrimaryNeoplasmsoftheGallbladder

PrimaryTumor(T)

TXPrimarytumorcannotbeassessedT0NoevidenceofprimarytumorTisCarcinomainsituT1TumorinvadeslaminapropriaormusclelayerT1a@@TumorinvadeslaminapropriaT1b@@TumorinvadesmusclelayerT2Tumorinvadesperimuscularconnectivetissue;noextensionbeyondserosaorintoliverT3Tumorperforatestheserosa(visceralperitoneum)ordirectlyinvadesoneadjacentorgan,orboth(extension2cmorlessintoliver)T4Tumorextendsmorethan2cmintoliver,and/orintotwoormoreadjacentorgans(stomach,duodenum,colon,pancreas,omentum,extrahepaticbileducts,anyinvolvementofliver)RegionalLymphNodes(N)NXRegionallymphnodescannotbeassessedN0NoregionallymphnodemetastasisN1Metastasisincysticduct,pericholedochaland/orhilarlymphnodes(i.e.,inthehepatoduodenalligament)N2Metastasisinperipancreatic(headonly),periduodenal,periportal,celiac,and/orsuperiormesentericlymphnodesDistantMetastasis(M)MXDistantmetastasiscannotbeassessedM0NodistantmetastasisM1DistantmetastasisStageGroupingTisN0M0StageIT1N0M0StageIIT2N0M0StageIIIT1N1M0T2N1M0T3N0M0T3N1M0StageIVAT4N0M0StageIVBAnyTN2M0AnyTAnyNM1

v励GもNv励G度20-30%xn砾wi钡もNv励Stage0BI-laparoscopiccholecystectomyStageIIBIII-radicalcholecystectomygv励G

]もNΤㄇfH|Ы场_oA┮HΤH[Wgv励Cgv励ノもNAo{subserosalIデApositivemargin┪Oぺ挡锣簿wAo{iH┑overallsurvivalCgv励]iノLkもNfHCて厩v励GGぃㄎ

x恨砾]BileDuctCarcinoma^

eēGx恨砾hoネ60-80烦Ak┦耕hCxずx恨砾35%AOw耕tA5~overallsurvival度2.8%x~x恨砾65%A5~overallsurvival17%

MI]lG]Ax挡ホBprimarysclerosingcholangitisBulcerativecolitisBxl挛PV]Clonorchissinensis^Bhn┦ef]polycysticdisease^单C

{{G90%HΤ峨┦独nA1/3HΤkh{AㄤL|Τブ涧oBGfぃnB砰U单C

E_GE_uㄣ]AWiBCTBMRCPMERCPCCA199i讽@wl萝]followup^A]iノPSC]primarysclerosingcholangitis^fHO_咯wx恨砾z匡uㄣ]screening^C

だ戳GTNMStagingforPrimaryNeoplasmsoftheExtrahepaticBileDucts

PrimaryTumor(T)TXPrimarytumorcannotbeassessedT0NoevidenceofprimarytumorTisCarcinomainsituT1TumorinvadessubepithelialconnectivetissueorfibromuscularlayerT1aTumorinvadessubepithelialconnectivetissueT1bTumorinvadesfibromuscularlayerT2TumorinvadesperifibromuscularconnectivetissueT3Tumorinvadesadjacentstructures:liver,pancrease,duodenum,gallbladder,colon,stomachRegionalLymphNodes(N)NXRegionallymphnodescannotbeassessedN0NoregionallymphnodemetastasisN1Metastasisincysticduct,pericholedochaland/orhilarlymphnodes(i.e.,inthehepatoduodenalligament)N2Metastasisinperipancreatic(headonly),periduodenal,periportal,celiac,and/orsuperiormesentericand/orposteriorpancreaticoduodenallymphnodesDistantMetastasis(M)MXDistantmetastasiscannotbeassessedM0NodistantmetastasisM1DistantmetastasisStageGroupingTisN0M0StageIT1N0M0StageIIT2N0M0StageIIIT1N1M0T1N2M0N1M0T2N2M0StageIVAT3AnyNM0StageIVBAnyTAnyNM1

v励G@Bxずx恨砾G(1)ResectableGち埃YL摧lf_Ail萝CYΤ摧lf_Aiσ{Aち埃A┪gv励A┪gv励[Wて厩v励]5-FU┪Gemcitabine^Av励l萝C(2)UnresectableGgv励A┪gv励[Wて厩v励]5-FU┪Gemcitabine^A┪cryotherapyA┪radiofrequencyablationC(3)MetastasisGて厩v励]5-FU┪Gemcitabine^A┪{刚喷A┪や┦励kC

GBx~x恨砾G(1)ResectableGもNち埃AY1.negativemargin-[诡┪chemoradiotherapy2.positivemargin-chemoradiotherapy(5FU)

*Huskell:adjuvantgv励ΘUa厨旧ぃ@ApEORTC{iH┑mediansurvivalAOJohnHopkinss{L┮tqCchemoradiotherapy]ΤH{ぃゑ虫Wgv励nC(2)UnresectableG惠n@xツまyCM钡chemoradiotherapy(5FU)Bて厩v励]5-FU┪Gemcitabine^B{刚喷┪や励kC

(3)MetastasisGxツまyAM钡て厩v励]5-FU┪Gemcitabine^B{刚喷B┪や励kC

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