前言目的通过临床
骨巨细胞瘤的检查,分析各CT灌注参数、最大强化速率(MER)与肿瘤的微血管密度(MVD)的关系;探讨MER在骨巨细胞瘤诊断中的应用价值;评价边缘-中心血流量差异率(Rrim-cenBF)、边缘-中心血容量差异率(Rrim-cenBV)在良恶性骨巨细胞瘤鉴别诊断中的应用价值。方法对24例病人的骨巨细胞瘤行CT灌注检查,其中恶性骨巨细胞瘤14例,良性骨巨细胞瘤10例。术后病理标本常规组织切片及SP免疫组织化学检查,单克隆抗CD34抗体标记血管,用Weidner技术计算肿瘤MVD。分析BF、BV、MER与肿瘤微血管密度的相关性;分析良恶性骨巨细胞瘤外周区与中央区之间BF、BV有无差异;比较良
恶性骨肿瘤之间MER、Rrim-cenBF、Rrim-cenBV的差异。结果24例骨巨细胞瘤均表现为高灌注,BF和BV图像上均可清楚显示肿瘤;骨巨细胞瘤的BF、BV和MER与MVD均呈正线性相关。MER能够准确地反映组织的血管化程度,但MER在良恶性骨巨细胞瘤之间存在较多重叠。Rrim-cenBF和Rrim-cenBV值在良恶性骨巨细胞瘤之间的差异具有显著性意义(P<0.01)。Rrim-cenBF和...
ObjectiveFortheclinicalCTexaminationofthepatientswithgiantcelltumorofbone:toanalysetherelationshipbetweentheCTperfusionparameters,themaximalenhancementrate(MER)andthemicrovesseldensity(MVD)ofthetumors;toinvestigatethediagnosticvalueofMERingiantcelltumorofbone;toassessdiagnosticvalueofrim-to-centerdifferentialbloodflowratio(Rrim-cenBF)andrim-to-centerdifferentialbloodvolumeratio(Rrim-cenBV)indifferentiatingbenignfrommalignantgiantcelltumorof...